Information For Physicians
Click below to view 4 short videos presented by Dr. Elizabeth Sussman PhD RD, Associate Professor of Nutrition and Dietetics specializing in renal nutrition and research, reviewing clinical data on the use of low protein diets supplemented with keto-analogues as a tool to slow the progression of CKD and maintain nutrition.
Low and very low protein diets supplemented with keto-analogues.
The use of a low or very low protein diet supplemented with a keto-analogue has been shown to reduce CKD progression, slow the onset of uremic symptoms, and improve nutritional parameters and markers. Please see the section below titled: "Recent clinical Data on the use of keto-analogues with LPD/VLPD" for clinical references and further information.
Keto-analogues of essential amino acids provide potential advantages for CKD patients. The Keto-acids in a keto-analogue lack the amino group bound to the alpha carbon of an amino acid so they can be converted to their respective essential amino acids without providing additional nitrogen.
Each dose of Ketorena contains 2100 mg or 2.1g of Keto & Amino Acids.
Please review the dosing and treatment protocol below from the IKABM. The dosing recommendations are to initiate a keto-analogue at 0.1g/kg BW/day.
A patient weighing 60kg would then take 0.1g x 60 = 6g or 6000mg. 1 scoop of Ketorena = 2100mg or 2.1g. 3 scoops = 6300mg or 6.3g. The dose would then be 1 scoop 3 times daily.
Patient types who may benefit from a low or very low protein diet supplemented with Ketorena:
The following beneficial effects may be found with a keto-analogue supplemented protein restricted diet:
The International Keto Analogue Board Meeting (IKABM) consensus statement on the